一种基因陷阱载体,包含LTR序列环绕着一个包含转录接受器和含有转录起始点的β-geo盒,以及一个包含PGK-btk的转录终止子的cassette,这个cassette特异性插入A亚型的外显子中。对大脑和肺组织的Northern和Western印迹分析显示,没有检测到A和B亚型的转录物和蛋白质对应物。(引用:J:83193)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
基因捕获载体的插入
--
1
--
20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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