在编码激酶域必需区域的外显子周围插入了LoxP位点。随后,通过Flp介导的重组,在ES细胞中移除了邻近的含弗雷特标签的诺卡因和胸腺嘧啶激酶元件,再经产生小鼠。(来源:J:83042)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
--
1
3
26

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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