Log In|Sign Up
中文
将含有EGFP和neo的靶向载体通过同源重组替换了一个3'端的exon 3区域。设计的打靶策略保留了PYRIN域，类似于已知的家族地中海热患者突变。对纯合突变小鼠的腹腔巨噬细胞进行 Western blot 分析后，检测到了含有GFP的截短蛋白。(来源：J:82763)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
