这个转基因表达的是经改良的cre重组酶(icre)开放阅读框,由远端的Lck启动子(dLck)控制。这种转基因在T细胞中主要在Tcra基因座重组后,且达到TCRhi发育阶段时表达。(来源:J:73479, J:99042)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F2
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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