Areg^Mcub

A T to G mutation occured in the G-GT splice donor site of exon 1 disrupting the donor site and resulting in the use of an alternative downstream splice site. The alternative splice site adds 22 nucleotides to the sequence resulting in a frame-shift and introducing a premature stop codon. Mcub is dominant modifier allele that causes a wavy coat in mice homozygous for the cub mutation. (J:211269)