在1B外显子的编码区域用荧光化诺卡因选择标记座替代后,产生了一种特异的等位基因突变。RT-PCR结果显示,插入序列上游编码A等位基因的部分被转录。通过RT-PCR分析,纯合突变小鼠中未检测到编码B等位基因的转录本。(来源:J:82249)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
6
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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