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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Ikbkb
tm2Cgn
Alias:
IKK2
flox
Ikbkb
tm1Mpa
Ikk2
FL
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基础信息
表型特征
文献报道
在经过靶向载体的同源重组,随后通过Cre介导的选择 cassette 剪切,产生转基因小鼠前,保留了包含6和7号外显子的2kb片段,该片段的两侧各有一个LoxP位点。(来源:J:77233)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2652651
B6.Cg-Thy1a
Targeted
插入
--
1
3
45
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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