Exon 2被替换了通过同源重组插入的诺姆西林选择座。 Western blot结果显示,纯合突变小鼠中没有这三种异构体。(来源:J:78451)
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Exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Western blot analysis indicated an absence of all three isoforms in homozygous mutant mice. (J:78451)