"使用小鼠CD4增强子序列、人类CD4启动子、8.8kb的HIV序列以及SV40的polyadenylation信号作为转录基因。这些增强子和启动子序列驱动在CD4+ T细胞和树突状细胞/巨噬细胞系的表达。HIV序列在env基因的第6400位插入了终止寡核苷酸。Northern blot分析显示,转录基因在胸腺中表达丰富,在淋巴结中表达适度,在肾脏、肺、肠道和肝脏中的表达则较弱。(来源:J:78756)"

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F2
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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