一段2.1千碱基的基因组DNA片段,包含第3外显子和大部分第4外显子,被替换为一个朝向着中心粒的 cassette,这个 cassette 包含了抗氨苄青霉素基因、一个loxP位点、Hprt微基因的5'端部分,以及Krt14-Agouti毛色突变基因。(来源:J:56548)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
插入,基因内删除
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1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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