包含启动子和exons 1和2的片段通过Cre介导的裁剪被去除。杂合ES细胞提取物的 Western blot 分析显示,这个等位基因不产生蛋白质。(来源:J:81637)
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A floxed fragment containing the promoter and exons 1 and 2 was excised via cre-mediated excision. Western blot analysis of heterozygous ES cell extracts indicated that protein was not produced from this allele. (J:81637)