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删除了341bp的外胚层增强子，并通过同源重组替换为一个含floxed neo cassette的元件。在正确靶向的细胞中短暂表达Cre重组酶，移除了floxed neo cassette，留下一个loxP位点取代了外胚层增强子。PCR基因型分析证实了纯合子动物中的突变基因。(来源：J:73524)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
