这个基因通过同源重组的方式,用一个诺卡因抗性质粒替换了编码494-619氨基酸(包括C1区域)的4个外显子,从而被打乱。通过 Western blot 用针对蛋白质极端N端和C端的抗体进行了缺失等位基因的验证。(来源:J:56513)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入,基因内删除
--
1
1
35

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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