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中文
这个基因通过同源重组，用1300bp的富含脯氨酸的外显子替换，插入了抗氨苄青霉素抗性基因 cassette，导致所有3个阅读框都产生了终止密码子。删除区域编码433个氨基酸，包含FH1域。对纯合突变体大脑RNA的Northern blot分析证实了野生型基因产物的缺失。观察到部分通过读通转录本，包含氨苄青霉素抗性基因 cassette。(来源：J:81246)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
