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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(CD2-MYC)1Jcn
Alias:
CD2-MYC
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基础信息
表型特征
文献报道
转基因包含了人类的MYC基因组序列,以及一个5.5kb的人类CD2主要调控区片段,用于在T淋巴细胞中驱动表达。Northern blot分析使用人类MYC第1外显子探针显示,转基因在所有胸腺肿瘤中表达,但健康组织中未见。(来源:J:81276)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
2448760
(C57BL/6J x CBA/Ca)F2
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1
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6
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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