转基因中包含一个79.5kb的P1插入,包含了完整的人类APOB基因。RNA slot blot结果显示,转基因在肝脏中表达,小肠和心脏有微量表达。对转基因动物的血浆进行 Western blot 分析,结果显示人类apo-B100是主要的转基因产物。(来源:J:81265)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x SJL)F1
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插入
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1
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33

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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