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中文
通过在566位点插入工程性终止密码子后，去除了loxP位点标记的诺卡因抗性 cassette，科学家们建立了一种Liddle综合症的小鼠模型，这通过Scnn1btm1Ipt个体与cre表达的TgN(EIIa-cre)C5379Lmgd线的杂交实现。对小鼠结肠和肾脏的Northern blot分析显示，突变个体中该基因的表达显著降低。（来源：J:59840）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
