在Exon 2,大约含有85%的编码序列被通过同源重组插入了诺卡因选择标记元件。通过对转基因纯合小鼠脑组织进行 Western blot 分析,未检测到蛋白质。神经元的免疫组化分析也证实了蛋白缺失。(来源:J:22966)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入,基因内删除
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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