Exon 1和1.6kb上游序列被通过同源重组插入了PGK-neo cassette。对孕鼠子宫组织的RNA进行Northern blot分析显示正常转录本缺失。用同源突变纯合胰腺和子宫组织的总膜提取物进行Western blot分析未检测到内源性蛋白质。(来源:J:80980)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count