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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Hspa2
tm1Dix
Alias:
Hsp70-2
-
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基础信息
表型特征
文献报道
内源性位点通过同源重组插入了诺卡因选择性 cassette,导致其失活。通过对纯合突变小鼠睾丸组织的Northern blot分析,未检测到转录本。睾丸切片的免疫染色显示生精管中缺乏正常蛋白。(来源:J:35110)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2447605
129P2/OlaHsd
Targeted
插入
--
1
--
8
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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