这个转基因包含了小鼠乳腺癌病毒(MMTV)启动子和部分小鼠Myc(骨髓瘤)致癌基因,去除了1号外显子。构建被命名为MTV-Xba myc。这位奠基个体携带有两个转基因的插入拷贝,随后通过杂交育种将其分别整合到了Tg(MMTV-cmyc)164-4aLed或Tg(MMTV-cmyc)164-4bLed品系中。(来源:J:29013)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CD-1 x C57BL/6J)F1
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插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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