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一段包含第3外显子和周围内含子部分的2.1kb片段，通过同源重组被一个neo cassette替换了。对纯合突变小鼠肝、肾、睾丸和肺组织的Northern和Western印迹分析未检测到转录或蛋白。对苯并[a]芘敏感的Nqo2活性测定结果显示，肾、睾丸和肺样本几乎完全丧失，而肝样本则减少了大约80%。作者报告说，剩余的活性在肝中被认为是相关蛋白的结果。(来源：J:80549)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
