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中文
使用了人类的THY1启动子和携带阿尔茨海默病患者中瑞典双突变(K670M和N671L)的人类APP序列，构建了转基因。对转基因动物脑组织切片的原位杂交分析显示，转基因表达在新皮质和海马区最高。(来源：J:44603)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
