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中文
内源性位点被新霉素选择 cassette 的插入所打断。信号肽序列通过跨膜区域的大部分被 neo 替换，导致框架移位突变，影响了胞质区的编码序列。对纯合突变小鼠胸腺细胞的 RT-PCR 检测未检测到转录本（J:80474, J:95221）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
