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中文
通过体外的Cre介导重组，在靶向的ES细胞中，删除了编码蛋白质激酶样域起始部分的外显子，这通过单个上游loxP位点和下游loxP标记的neor-tk cassette的3'端loxP位点实现。杂合子小鼠的交配后代中无纯合子出现，这表明该基因或蛋白质的功能受到了破坏。(来源：J:71950)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
