使用了1kb大小的转基因小鼠Ucp1 cDNA,它被一个来自大鼠Mylk2启动子的控制。加入了人类ALB内含子和人类GAPD的终止及polyadenylation序列到这段鼠源序列中。逆转录PCR分析证实了在骨骼肌中表达,但在检查的其他组织中未见表达。(来源:J:65242)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F1
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插入
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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