在含有Hoxdtm5Ddu突变体的ES细胞中,插入了一个内含子lacZ后面跟着一个floxed neo基因。在体外,floxed neo cassette被剔除了,留下Hoxd13基因上的lacZ报告基因,同时Hoxd11和Hoxd12基因被反向的loxP座 flank着。(来源:J:66264)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
插入
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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