一段1.2kb的片段,位于Evx2和Hoxd13之间,包含区域12,被替换成了一个含neo标记的敲除 cassette。这些带有这个突变基因的鼠被与表达Cre重组酶的转基因鼠杂交,产生了Evx2/Hoxd13tm3.1Ddu小鼠(J:80084)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intergenic deletion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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