通过体内Cre介导的重组,从Cer1tm1Rph中去除了含有的floxed hygromycin基因,其替换的首编码外显子被移除。插入的lacZ基因仍位于编码起始甲硫氨酸、信号肽、前序和第一个胱氨酸簇的序列位置。lacZ的表达模式与内源基因相似。(来源:J:62081)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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