假基因是通过将Schmidt-Ruppin菌株的病毒SRC编码序列插入GFAP的第1外显子构建的。GFAP启动子驱动在大脑星形胶质细胞中表达该转基因。对转基因动物大脑RNA的RT-PCR分析证实了转基因的表达。此外,转基因在肺、胸腺、脾和性腺中也得到了检测。(来源:J:40335)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x C3H)F1
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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