这种突变体来自Rb1tm1Jyjw。在第25号内含子中去除的floxed neo cassette,是通过将Rb1tm1Jyjw动物与Cre表达线TgN(Prm-cre)58Og杂交得到的。后代中包含在第25号外显子的天冬氨酸到alanine的替换变异,以及诊断用的EcoRI酶切位点在第24号内含子。(来源:J:80087)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入
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1
14
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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