一段1.1kb的基因组区域,包含5' DNase I敏感性位点2(HS2),通过同源重组被一个由FRT座和诺卡因抗性基因座组成的neo标记替换。通过Southern blot分析,成功基因靶向在突变动物中得到了确认。(来源:J:28981)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJaeSor
Targeted
载体插入引起的破坏
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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