原生地基因产生的三种异构体表达被替换为诺卡因选择标记座的结果被干扰了。 Western blot分析表明,尽管突变小鼠中存在116 kD的周围神经和71 kD的非肌肉异构体,但427 kD的 dystrophin、260 kD的视网膜和140 kD的异构体缺失了。(来源:J:43164)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
插入,基因内删除
--
1
18
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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