在基因的第3外显子位置插入了新霉素 cassette,对同卵突变小鼠的肝脏 RNA 北方印迹和总肝脏蛋白 Western 印迹均未检测到针对该基因的可检测转录物或蛋白质。(来源:J:54684)
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A neomycin cassette replaced exon 3 of the gene. Northern blots of liver RNA and Western blots of total liver protein from homozygous mutant mice showed no detectable transcript or protein, respectively, for the targeted gene. (J:54684)