构建中包含CMV启动子、大鼠Nell1基因cDNA以及SV40polyadenylation序列的转基因元件随机整合到了小鼠基因组中。Southern blot结果显示,创始系中有50到100个这种构造的插入。表达情况通过RT-PCR和免疫组化分析得到了确认(来源:J:79106)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x C3H
--
插入
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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