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经过修改的Map3k8 cDNA，其中病毒LTR序列替换了第八个外显子，并连接至一个在胸腺细胞中活跃的lck近端启动子。这个转基因编码了一个缺失23个羧基端序列的片段，这与Moloney小鼠白血病病毒（MoMLV）整合到Map3k8位点后产生的相似截短蛋白相匹配。表达分析证实了截短蛋白的表达。(来源：J:39450)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
