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在体内Cre介导的重组中，去除了Esrtm1Lja中的floxed neo cassette。对第207和208位的谷氨酸到异亮氨酸和甘氨酸到异亮氨酸的错义突变保持不变。通过肝组织的RT-PCR和 Western blot分析，验证了突变转录本和蛋白的表达。(来源：J:79228)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
