在exon 2的3'端,通过同源重组插入了诺卡因选择标记基因座。被删除区域编码了外周细胞膜的氨基端区域、跨膜区1和2,以及第一个内膜段。通过Northern blot对来自转基因纯合小鼠纹状体的RNA进行分析,转录本未被检测到。(来源:J:79483)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
1
14

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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