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中文
这个基因通过将exon 3编码催化部位的天冬氨酸区域替换为lacZ-neo cassette，导致了失活。构建物在所有3个阅读框中引入了终止密码子。对大脑RNA的Northern blot检测证实了纯合突变动物中基因表达的缺失。对突变大脑的X-gal染色未发现任何lacZ表达。（来源：J:71533）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
