这种等位基因来自Hoxb4tm2Nrm。来自杂合Hoxb4tm2Nrm雌雄交配胚胎的注射了Cre表达质粒,以去除首编码段的floxed neo cassette。删除后,第一编码外产生了一个78bp插入,包含一个loxP位点。这个78bp插入在Hoxb4转录本的框架内有一个终止密码子。(来源:J:71389)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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