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中文
一种基因陷阱载体，包含两个LTR元件，它们环绕着一个包含转录接受器和含有PGK-puromycin抗性元件的β-geo盒，该元件的转录起始点位于第一个编码外显子下游的内含子中。对肾组织RNA的Northern blot分析证实了纯合突变小鼠中正常转录本的缺失。β-geo的表达被检测到，并推测由内源性启动子驱动。虽然在ES细胞中检测到了来自内部PGK启动子的表达，这有助于确定中断的基因，但在来自小鼠的RNA（通过Northern blot和RT-PCR分析）中并未发现这种表达。(来源：J:74230)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
