在Tcra-C元素C1上游插入了loxP位点,然后通过同源重组在C3和C4之间插入了loxP标记的neo基因。针对的ES细胞的暂时转染去除了neo cassette,保留了由C1、C2和C3被loxP位点环绕的条件性Calpha基因等位基因。(来源:J:79298)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion, Intergenic deletion
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8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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