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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Plcg1
tm2Gcrp
Alias:
Plcg1-
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基础信息
表型特征
文献报道
对X区域和两个SH3域进行序列编码的插入了一个包含lacZ和neo的 cassette后,这两个区域和功能被删除。仅检测到了在来自纯合突变小鼠的MEFs中提取的蛋白质片段。这与TV-II导向载体相关(J:39281)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2388142
129S6/SvEvTac
Targeted
载体插入引起的破坏
--
1
1
3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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