通过同源重组,基因的整个编码区域被替换了 neoantigen 抗性载体。对于纯合突变动物大脑 mRNA 的Northern印迹分析未检测到基因表达。对纯合动物大脑组织的免疫组化分析也证实了基因表达的缺失。(来源:J:68831)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
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1
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12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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