Exon 1被一个包含lacZ和neo基因的 cassette 打断了。通过对纯合突变小鼠大脑提取物的 Western blot 分析,没有检测到蛋白质。(来源:J:79099)
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Exon 1 was disrupted with a cassette containing lacZ and neo genes. Protein was undetected by Western blot analysis of brain extracts from homozygous mutant mice. (J:79099)