Exon 2被通过同源重组插入了诺美西林选择标记 cassette。在用针对氨基酸端的抗体检测中,纯合突变小鼠中未检测到蛋白质。此外,通过放射性标记ligands的 autoradiographic 分析,确认了对药理定义的受体 delta1 和 delta2 的ligand结合缺失。(来源:J:57886)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
插入,基因内删除
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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