整个基因(包括exon 1-8)通过同源重组被替换了抗氨苄青霉素的基因。通过 Western blot 分析,证实了纯合突变动物中基因表达的缺失。(来源:J:53628)
查看原文 参与反馈
The entire gene (exon 1-8) was replaced with a neomycin resistance gene via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by Western blot analysis. (J:53628)