这个基因在第793位碱基通过插入一个PGK-neo cassette发生了突变。通过western blot分析,没有在纯合突变动物的胸腺细胞和脾脏的B细胞和T细胞中检测到完整的或部分的蛋白质产物。(来源:J:79324, J:97055)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
--
1
--
85

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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