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中文
这个基因在exon 2位置插入了PGK-neo cassette，导致其功能受损。通过对肺组织的Northern blot分析，没有检测到纯合突变动物的成熟mRNA，但发现了一个较弱的、较小尺寸的带。RT-PCR和测序结果显示，这个产物是经由exon 1到exon 3的替代性剪接转录本，跳过了exon 2。在纯合突变动物的肺泡灌洗液中未检测到蛋白质产品。（来源：J:69619）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
