一种诺他霉素抗性基因座替换了包括最后一个外显子的序列,该外显子编码激酶域的末端和细胞质尾部。RT-PCR结果显示,这个突变等位基因产生了表达缺失细胞质激酶域序列的突变转录本。(来源:J:53423, J:153843)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
不确定
1
4
48

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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